Synthesis, Characterization and Antimicrobial Activity of Coordination Compounds of Thiosemicarbazone Moiety

Authors

  • Javed G. Mahetar  Inorganic Section, Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India
  • Rohit B. Manawar  Inorganic Section, Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India
  • Chandan T. Pashavan  Inorganic Section, Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India
  • Manish K. Shah  Inorganic Section, Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

Abstract

The synthesis and spectral analysis of coordination complexes of Copper(II), Nickel(II), Cobalt(II), Zinc(II) 1-(3-bromo-4-hydroxy-5-methoxybenzylidene)-4-(4-chlorophenyl)thiosemicarbazide was synthesized. Elucidation of ligand and coordinated compounds were done using Mass spectroscopy, IR, 1H NMR, 13C NMR spectroscopy, elemental analysis (C, H, N, S), and UV–Visible spectroscopy. All Metal complexes were prepared in a molar ratio of 1:2 (M:L) as stoichiometry data disclose. Thermo gravimetric analysis (TGA) was conducted to support the structures of all four metal complexes. Antibacterial and antifungal screenings of these coordinated compounds reveal good to excellent results with respect to ligand and standard drugs.

International Journal of Scientific Research in Chemistry

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Published

2018-02-26

Issue

Volume 3, Issue 3, January-February-2018

Section

Research Articles

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Copyright (c) IJSRCH

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Javed G. Mahetar, Rohit B. Manawar, Chandan T. Pashavan, Manish K. Shah, " Synthesis, Characterization and Antimicrobial Activity of Coordination Compounds of Thiosemicarbazone Moiety, International Journal of Scientific Research in Chemistry(IJSRCH), ISSN : 2456-8457, Volume 3, Issue 3, pp.13, January-February-2018.