Design, Synthesis and Biological Studies of Some ‘N’ and ‘S’ Based Heterocycle

Abstract

Novel series of ‘N’ and ‘S’ bridged heterocycle comprising oxadiazole, piparazine and variour amine to principal moiety 2,4,6-trichloro pyrimidine have been synthesized. Chlorine atoms of 2,4,6-trichloro pyimidine has been subjected to nucleophile substitution sequentially varying condition to get the target molecule. The resulted compounds were characterized by IR, mass and 1H NMR spectroscopy and further evaluated for antimicrobial activity against different strains.