Synthesis and Biological Activities of Metal Complexes

Abstract

Transition metal (II) complexes, [ML2(H2O)2] 1-4, were synthesized by the reaction of MCl2.nH2O (M = Cu, Ni, Co, Mn) and the schiff base ligand. Schiff base were synthesis by condensation of 2-hydroxy Aceto phenone with aromatic amines. Synthesized complexes were characterized by elemental analysis, FT-IR spectra and TGA. The Schiff base ligand and its complexes have been tested in vitro antibacterial activity against bacteria, viz. Escherichia coli MTCC – 443, Pseudomonas aeruginosa MTCC – 1688, Bacillus subtilis MTCC – 441, Staphylococcus aureus MTCC – 96 and fungal strain Aspergillus niger MTCC – 282. It has been found that the complexes have higher activity than the corresponding schiff base ligand in comparison with the same bacterial and fungal strains.