Greener and Novel Routes Towards the Synthesis of Ibuprofen

Panjikar Padmini C

doi:10.32628/IJSRCH183513

Greener and Novel Routes Towards the Synthesis of Ibuprofen

Authors(1) :-Panjikar Padmini C

The traditional method of manufacture of drug ibuprofen is that of six steps. But in greener method we have synthesized the same in only single step. The traditional method of manufacture of drug ibuprofen is that of six steps. But in greener method we have synthesized the same in only single step. The synthesis of the drug was from isobutyl benzene and 2-hydroxy propanoic acid. It is widely used as an important pain killer in therapeutic field.

Authors and Affiliations

Panjikar Padmini C
Assistant Professor, Parvatibai Chowgule College, Margao, Goa

Drug, Greener Method, Ibuprofen, Pain killer,Therapeutic Field.

Anastas PT, Warner JC. Green Chemistry: Theory and Practice. Oxford University Press, New York, 1998.
Warren D. Green Chemistry. A Teaching Resource. Royal Society of Chemistry, Cambridge, 2001.
Clark J, Macquarrie D. Handbook of Green Chemistry and Technology. Blackwell Publishing, Abingdon, Oxfordshire, 2002.
Poliakoff M, Licence P. Green Chemistry. Nature 450: 810-812, 2007.
Tundo P, Anastas PΤ (Eds). Green Chemistry: Challenging Perspectives. Oxford University Press, Oxford, UK, 2000.
Sheldon RA, Arends I. Green Chemistry and Catalysis. Wiley–VCH, Indianapolis, USA, 2006.
Royal Society of Chemistry (RSC). Ibuprofen- a case study in green chemistry. RSC publications, Cambridge, UK (http://www.rsc.org/education/teachers/learnnet/ibuprofen/ibuprofen.pdf)
The BHC Company Synthesis of Ibuprofen. From Cann MC, Connelly ME. Real World Cases in Green Chemistry. American Chemical Society, Washington, DC, 2000. (http://alpha.chem.umb.edu/chemistry/ orgchem/greensynthiboprufencasestudy.pdf
"Green Chemistry". United States Environmental Protection Agency. 2006-06-28. Retrieved 2011-03-23.
Sheldon, R. A.; Arends, I. W. C. E.; Hanefeld, U. (2007). "Green Chemistry and Catalysis". doi:10.1002/9783527611003. ISBN 9783527611003.
Clark, J. H.; Luque, R.; Matharu, A. S. (2012). "Green Chemistry, Biofuels, and Biorefinery". Annual Review of Chemical and Biomolecular Engineering 3: 183–207. doi:10.1146/annurev-chembioeng-062011-081014. PMID 22468603.
Cernansky, R. (2015). "Chemistry: Green refill". Nature 519 (7543): 379. doi:10.1038/nj7543-379a.
Sanderson, K. (2011). "Chemistry: It's not easy being green". Nature 469 (7328): 18. doi:10.1038/469018a.
Poliakoff, M.; Licence, P. (2007). "Sustainable technology: Green chemistry". Nature 450 (7171): 810–812. doi:10.1038/450810a. PMID 18064000.
Clark, J. H. (1999). "Green chemistry: Challenges and opportunities". Green Chemistry 1: 1. doi:10.1039/A807961G.

Publication Details

Published in : Volume 1 | Issue 2 | 2016
Date of Publication : 2016-11-30
License: This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 11-14
Manuscript Number : IJSRCH183513
Date Written : 2016-11-25
Publisher : Technoscience Academy

ISSN : 2456-8457

Suggested Citation :

Panjikar Padmini C, "Greener and Novel Routes Towards the Synthesis of Ibuprofen", International Journal of Scientific Research in Chemistry (IJSRCH), ISSN : 2456-8457, Volume 1, Issue 2, pp.11-14, .2016
URL : https://ijsrch.com/IJSRCH183513

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Manuscript Number : IJSRCH183513

Greener and Novel Routes Towards the Synthesis of Ibuprofen