Novel 4- Thiazolidinones and Its Styryl Derivatives : Design, Synthesis and Characterization of Biologically Potent Antibacterial Agents

Abstract

Two series of some new 4-thiazolidinones and styryl containing derivatives were designed and synthesized, screened for their antimicrobial activities. The structures of the compounds were elucidated with the aid of IR, 1H NMR spectroscopy, and elemental analysis. The antimicrobial activity of the compounds were tested against four bacteria (Staphylococcus aureus MTCC 443 and Staphylococcus pyogenus MTCC 443) and two Gram-negative (Escherichia coli MTCC 442 and Pseudomonas aeruginosa MTCC 443).