Synthesis and Characterizations of Oxazolo Thiazolo Pyrimidine Derivatives as Biological Active and Antiinfective Agents
Keywords:
Oxazolo Pyrimidine, Antibacterial Activity, Biginelli Reaction.Abstract
Pyrimidines are those molecules that make our life possible being the building blocks of DNA and RNA. Pyrimidine plays a significant role among other heterocycles. Literature survey reveals that partially reduced pyridine and Pyrimidine derivatives are known to have antihypertensive property. Pyrimidine nucleus was synthesized by Biginelli reaction. The aim of this study was to synthesize and introduce many title compound evaluate them for their antibacterial and antifungal activity. The structures of all title compounds have been confirmed on the basis of their analytical, IR and NMR spectral data. The title compounds have been tested for antibacterial activities against different strains of bacteria.
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