Synthesis, Characterization and Antimicrobial activity of some novel 1, 3 Oxazine Derivatives having benzyloxyhydroxymonoiodo raceacetophenone moiety

Authors

  • S. S. Sipai  Department of Chemistry, Shri U. P. Arts, Smt. M. G. Panchal Science & Shri V. L. Shah, Commerce College, Pilvai, India
  • S. S. Shah  Department of Chemistry, Shri U. P. Arts, Smt. M. G. Panchal Science & Shri V. L. Shah, Commerce College, Pilvai, India
  • Deep S. Shah  Department of Chemistry, Shri U. P. Arts, Smt. M. G. Panchal Science & Shri V. L. Shah, Commerce College, Pilvai, India

Keywords:

Chalcones, Phenone Derivatives, Oxazine, Antibacterial And Antifungal Activity

Abstract

Oxazine derivatives has wide applications in Pharmaceutical and medicinal chemistry. 2-(2-amino-6-(sub-phenyl)-6H-1, 3-oxazin-4-yl)-5-(benzyloxy)-4-benzyloxy)-4-iodophenol (C1-10) were synthesized by condensation and cyclization with urea in ethanolic sodium hydroxide solution. Compounds (B1-10) were synthesized by coupling with aromatic substituted aldehyde. All the synthesized compounds were characterized by elemental analysis, IR, 1H NMR, 13C NMR spectra. Further, the prepared compounds were screened for antibacterial and antifungal activity.

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International Journal of Scientific Research in Chemistry

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Published

2019-12-30

Issue

Volume 4, Issue 6, November-December-2019

Section

Research Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
S. S. Sipai, S. S. Shah, Deep S. Shah, " Synthesis, Characterization and Antimicrobial activity of some novel 1, 3 Oxazine Derivatives having benzyloxyhydroxymonoiodo raceacetophenone moiety, International Journal of Scientific Research in Chemistry(IJSRCH), ISSN : 2456-8457, Volume 4, Issue 6, pp.35-43, November-December-2019.