Pharmacopeial Standard Development, HPTLC. Fingerprinting And Physicochemical Research Studies of Polyherbal Classical Drug Raughan-E-Muqawwi-E-Dimagh- A Brain Booster Medicated Oil

Authors

  • Pawan Kumar Sagar  Drug Standardization Research Institute, (Under CCRUM, Ministry of AYUSH., Govt. of India), PCIM&H Campus, IInd Floor, Kamla Nehru Nagar, Ghaziabad, U.P., India.
  • N. Z. Ahmed  Central Council for Research in Unani Medicine,(Under Ministry of AYUSH., Govt. of India),61-62, Institutional Area, Janakpuri, New Delhi, India
  • A. S. Khan  Drug Standardization Research Institute, (Under CCRUM, Ministry of AYUSH., Govt. of India), PCIM&H Campus, IInd Floor, Kamla Nehru Nagar, Ghaziabad, U.P., India.
  • R. P. Meena  Central Council for Research in Unani Medicine,(Under Ministry of AYUSH., Govt. of India),61-62, Institutional Area, Janakpuri, New Delhi, India
  • M. W. Ahmed  Drug Standardization Research Institute, (Under CCRUM, Ministry of AYUSH., Govt. of India), PCIM&H Campus, IInd Floor, Kamla Nehru Nagar, Ghaziabad, U.P., India.
  • S. A. Ansari  Drug Standardization Research Institute, (Under CCRUM, Ministry of AYUSH., Govt. of India), PCIM&H Campus, IInd Floor, Kamla Nehru Nagar, Ghaziabad, U.P., India.
  • S. Sajwan  Drug Standardization Research Institute, (Under CCRUM, Ministry of AYUSH., Govt. of India), PCIM&H Campus, IInd Floor, Kamla Nehru Nagar, Ghaziabad, U.P., India.
  • S. Kashyap  Drug Standardization Research Institute, (Under CCRUM, Ministry of AYUSH., Govt. of India), PCIM&H Campus, IInd Floor, Kamla Nehru Nagar, Ghaziabad, U.P., India.

Keywords:

Raughan-e-Muqawwi-e-Dimagh (REMED), Anti-amnesic, Medicated Brain booster oil, development of pharmacopeial standards, physicochemical, comparative screening, quality control and assurance.

Abstract

Medicated Brain booster oil drug Raughan-e-Muqawwi-e-Dimagh a classical formulation used in the treatment of Brain Weakness, Insomnia, Amnesia and other Neurological disorders from since ancient time. Three drugs samples of REMED taken into these studies which 3 Batches were prepared B1,B2 and B3. and developed from applied SOP. on the basis of authenticated classical texts and literature of standard methods. The quality control & quality assurance studies were conducted in accordance to the WHO., AOAC., IPC. and UPC., approved guidelines. The physicochemical data showed Extractive, %, w/v. (100), that the drug samples contained Petroleum ether(60-80°C), Acid value (69.12), Iodine value (23.99), Peroxide value(14.86), Saponification Value (248.29), Unsaponifiable matter,% (2.36),Refractive index (1.4657),Weight per ml.(gm.) (0.9006),Test for presence of Arachis oil, Cotton seed oil and Mineral oil both are found negatives and various bioactive phytochemical screening examined were assessed in REMED. HPTLC. studies of alcohol extracts of different Batches B1.B2 and B3 of REMED. Classical formulation showed various spots at 366nm (UV. region), under exposed to Vinyl - Sulfuric acid reagent. derivatized obtained with equate, best separation using selected suitable solvent system of mobile phase. The quality control studies results revealed the absence of hazardous and toxic contamination from the drug samples. Moreover the obtained research studies data and comparative screening will provide the referential supportive information in the development of pharmacopeial standard monographs, identification of classical formulation, reinvestigation, quality assurance and pharmacovigilance and validation of the Quality standard of REMED classical drug providing the quality medicine to needful public mass of the World.

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International Journal of Scientific Research in Chemistry

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2023-08-30

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Volume 8, Issue 4, July-August-2023

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Research Articles

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[1]
Pawan Kumar Sagar, N. Z. Ahmed, A. S. Khan, R. P. Meena, M. W. Ahmed, S. A. Ansari, S. Sajwan, S. Kashyap, " Pharmacopeial Standard Development, HPTLC. Fingerprinting And Physicochemical Research Studies of Polyherbal Classical Drug Raughan-E-Muqawwi-E-Dimagh- A Brain Booster Medicated Oil , International Journal of Scientific Research in Chemistry(IJSRCH), ISSN : 2456-8457, Volume 8, Issue 4, pp.53-69, July-August-2023.