Efficient and Environmentally Benign Synthesis of Quinoxaline Catalysed by Fruit Juice

Authors

  • Anis Ahmed Sheikh  Department of Chemistry, Maulana Azad College of Arts, Science and Commerce, Aurangabad, Maharashtra, India
  • Patel Shaukat Karimkha  Department of Industrial Chemistry, Adarsh Senior College, Omerga Dist, Osmanabad, Maharashtra, India
  • Sayyad Sultan Kasim  Department of Chemistry, Maulana Azad College of Arts, Science and Commerce, Aurangabad, Maharashtra, India

Keywords:

Benzene 1,2 Diamine,1,2 Dicarbonyl Compounds ,Orange Juice

Abstract

Quinoxaline is one of the most important nitrogen heterocycle having diverse applications in medicinal field. In spite of importance of several methodologies proposed by researchers these methods are still having some limitations in view of green chemistry principles. In this research paper we have proposed the efficient and environmentally benign orange juice catalysed green synthesis of Quinoxaline. The condensation of 1,2 dicarbonyl compound with 1.2 diamine has been carried out in presence of orange juice and the results obtained are tabulated. The mild reaction, short reaction time, easy work and good to excellent yield are some salient features of this protocol.

References

  1. S. Srivastava, J. Banerjee, N. Srestha. (2014).IOSR Journal Of Pharmacy. 4(12),17-27.
  2. A. Hasaninejad, A. Zare, M.R. Mohammadizadeh, M. Shekouhya (2008) ARKIVOC xiii, 28-35.
  3. S. Rong, X.Yu, W. Qinjie, X. Qing,Y. Qiaojun, H. Bo, H. Yongzhou. (2007). Drug Discov. Ther.1(2),119-123.
  4. M.M. Hossain, M.H. Muhib, M.R. Mia, S. Kumar, , S.A. Wadud. (2012).Bangladesh Med Res Counc Bull.(38).47-50
  5. A.F. Crowther, F.H.S. Curd, D.G.Davey, G.J. Stacey. (1949).Chem. Soc. 1260-1262.
  6. J.B. Rangisetty, C.N. Gupta, V.H. Prasad, A.L. Srinivas, P. Sridhar, N. Parimoo, Veeranjaneyulu, P.(2001).A. J. Pharmacy, Pharmacology. 53, 1409 -1413.
  7. D.P. Singh, S.R. Hashim, R.G.Singhal (2010). International Journal of Drug Development & Research 2(4),187.
  8. M. Alswah, A. Ghiaty, A. El-Morsy, K. El-Gamal. (2013).Hindawi Publishing Corporation. http://dx.doi.org/10.1155/2013/587054
  9. V.K. Tandon, D.B. Yadav, H.K. Maurya, A.K. Chaturvedi, P.K. Shukla. (2006). Med. Chem.14, 6120-6126. DOI: 10.1016/j.bmc.2006.04.029
  10. S. Biswas, S.Batra. (2013). European Journal Organic Chemistry. 4895–4902.
  11. Anis Ahmed Sheikh et al. Int. J. S. Res. Sci. Engg. Technol. September-October- 2018; 4(10): 176-180
  12. Tai-kun Huang, Rui Wang, Lin Shi, Xiao-xia Lu. (2008).Catalysis Communications. 9, 1143–1147
  13. P. Ghosh, A. Mandal. (2012).Tetrahedron Lett. 53,6483-6488.
  14. F.W. Wu, R.S. Hou, H.M. Wang, I. J. Kang, L.C.Chen. (2011) Heterocycles.. 83, 2313-2320.
  15. S. S. Kasim, S. Fazil, A. A. Sheikh.(2018) Int. Jour. of Res. Cult. Soc. 2.2, 31-35
  16. D.Q., Shi, G.L. Dou, (2008). Synth. Commun. 38, 3329.

International Journal of Scientific Research in Chemistry

Downloads

Published

2020-01-29

Issue

Volume 5, Issue 1, January-February-2020

Section

Research Articles

License

Copyright (c) IJSRCH

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Anis Ahmed Sheikh, Patel Shaukat Karimkha, Sayyad Sultan Kasim, " Efficient and Environmentally Benign Synthesis of Quinoxaline Catalysed by Fruit Juice, International Journal of Scientific Research in Chemistry(IJSRCH), ISSN : 2456-8457, Volume 5, Issue 1, pp.01-05, January-February-2020.