Antimicrobial Activity of 1, 3, 4-Thiadiazole & Its Derivative

Abstract

For a long time, researchers have been fascinated by the chemistry of heterocyclic compounds. The 1,3,4-thiadiazole heterocyclic nucleus is a crucial family of compounds for the development of new medications. The synthesis of novel thiadiazole derivatives, as well as the investigation of their chemical and biological activity, has grown increasingly relevant in recent decades. In medicinal chemistry, the search for antibacterial drugs with improved selectivity and lower toxicity is still a hot area. Bacterial resistance to various antibiotics has been recognised as a barrier to infection treatment, spurring the development of new antimicrobial drugs. In recent years, various research programmes have focused on novel 1,3,4-thiadiazole molecules having a wide range of biological activity.