Knowledge, Attitude and Practice of antibiotics Resistance survey among healthcare professionals in selected health centers in Greater Monrovia, Liberia

Authors

  • Plenseh Diana Paye  Assistant Professor & Chair of Medicinal Chemistry, School of Pharmacy, University of Liberia
  • James McClain  Assistant Professor of Physical Chemistry, Dean College of Science, Technology, Environment, and Climate Change, University of Liberia

Keywords:

Greater Monrovia, Antimicrobial resistance, antibiotics, Health workers, John F. Kennedy Medical Centre, Redemption Hospital, Liberia

Abstract

Background: Antimicrobial resistance is a global challenge as it leads to a high risk of mortality and a more vital economic issue. Many programs and research have been implemented to improve the irrational use of antibiotics associated with reducing antimicrobial resistance.
Objectives: This cross-sectional study aims to evaluate the knowledge, attitude, and practice of anti-microbial resistance survey among health workers from two selected health centers in Liberia - Redemption Hospital and the John F. Kennedy Medical Centre.
Methods: The cross-sectional study used a survey questionnaire on antimicrobial resistance. One hundred and twenty-six health workers comprised of physicians, pharmacists, and nurses were recruited from the two health centers.
Results: A response rate of N = 29 (physicians), N = 16 (pharmacists) and N = 81 (nurses) was achieved for the health workers respectively. The results show that antibiotic is fundamentally used in the treatment of viral infection, 93.1% (N=27) of the physicians, 87.5% (N=14) of the pharmacists, and 77.8% (N=63) correctly responded to the questions. About 86% (N=25) of physicians, 81% (N=13) of the pharmacists, and 61.7% (N=50) disagree that antibiotic resistance is not an issue in Liberia. The proportion of health workers who agreed that antibiotics are not the ideal medication in the curing of fungal infections are 86% (N=25) physicians, 75% (N=12) pharmacists, and 64% (N=52) nurses. Relative to the testing, health workers' knowledge of antimicrobial resistance, 37.9% (N=11), 43.8% (N=7), and 32.1% (N=26) of the physicians, pharmacists, and nurses respectively agreed that bacteria that are resistant to antibiotics could be spread from person to person.
Conclusions: This study revealed important information on knowledge, attitude, and practice of physicians, pharmacists, and nurses about AMR that could be useful for designing a knowledge base research.

References

  1. Abera, B., Kibret, M., & Mulu,Wondemagegn. (2014). Knowledge and beliefs on antimicrobial resistance among physicians and nurses in hospitals in Amhara Region, Ethiopia. BMC Pharmacology and Toxicology , 15, 26.
  2. Apisarnthanarak, A., Tunpornchai, J., Tanawitt, K., & Mundy, L. M. (2008). Nonjudicious dispensing of antibiotics by drug stores in Pratumthani, Thailand. Infection Control & Hospital Epidemiology. American journal of infection control, 29(6), 572-575.
  3. Bayeh, A., Mulugeta, K., & Wondemagegn, M. (2014). Knowledge and beliefs on antimicrobial resistance among physicians and nurses in hospitals in Amhara Region, Ethiopia. BMC Pharmacology and Toxicology ., 15-26.
  4. Bernabe, K. J., Langendorf, C., Ford, N., Ronat, J.-B., & Murphy, R. A. (2017). Antimcrobial resistance in West Africa: a systemic review and meta-analysis. International Journal of Antimicrobial Agents, 629-639.
  5. Chalker, J., Ratanawijitrasin, S., Chuc, N., Petzold, M., & Tomson, G. (2005). Effectiveness of a multi-component intervention on dispensing practices at private pharmacies in Vietnam and Thailand—a randomized controlled trial. Social science & medicine, 60(1), 131-141.
  6. Chen, C. (2005). Behaviour, attitudes and knowledge about antibiotic usage among residents of Changhua, Taiwan. J Microbiol Immunol Infect., 38, 53-59.
  7. Firouzabadi, D., & Mahmoudi, L. (2019). Knowledge, attitude, and practice of health care workers towards antibiotic resistance and antimicrobial stewardship programmes: A cross-sectional study. Journal of Evaluation in Clinical Prctices, 01- 12. doi:10.1111/jep.13177
  8. Garcia, C., Llamocca, L. P., Garcia, K., Jimenez, A., Samalvides, F., Gotuzzo, E., & Jacobs, J. (2011). Knowledge, attitude and practice survey about antimicrobial resistance and prscribing among physicians in hospital setting in Lima, Peru. BMC Clinical Pharmacology Journal, 02-08.
  9. García, C., Llamocca, L. P., García, K., Jiménez, A., Samalvides, F., Gotuzzo, E., & Jacobs, J. (2011). Knowledge, attitudes and practice survey about antimicrobial resistance and prescribing among physicians in a hospital setting in Lima, Peru. BMC Clinical Phamacology , 01-08.
  10. Gothwal, R., & Shashidhar, T. (2015). Antibiotic pollution in the environment: a review. CLEAN – Soil, Air, Water, 43, 479–489.
  11. Grigoryan, L., Burgerhof, J., Haaijer-Ruskamp, F., Degener, J., Deschepper, R., Monnet, D.,. group, S. (2007). Is self- medication with antibiotics in Europe driven by prescribed use? J Antimicrob Chemother. , 59, 152-6.
  12. Guerra, C., Pereira, C., Neves, N. A., Cardo, D., & Correa, L. (2007). Physicians’ perceptions, beliefs, attitudes and knowledge concerning antimicrobial resistance in a Brazilian teaching hospital. Infect Control Hosp Epidemiol, 28, 1411–1414.
  13. Howard, P., Ashiru-Oredope, D., & Gilchrist, M. (2018). . Time for pharmacy to unite in the fight against antimicrobial resistance. Stroke , 13.
  14. Kamulegeya, A., William, B., & Rwenyonyi, C. (2011). Knowledge and antibiotics prescription pattern among ugandan oral health care providers: a cross-sectional survey. Dent Res Dent Clin Dent Prospects., 5(2), 61.
  15. Kheder, S. (2013). Physcians knowledge and perception of antimicrobial resistance: A survey in Khartoum Stata Hospital settings. Br J Pharmaceut Res., 3, 347-362.
  16. Kotwani, A., Wattal, C., Katewa, S., Joshi, P., & Holloway, K. (2010 ). Factors influencing primary care physicians to prescribe antibiotics in Delhi India. Family practice., 27(6), 684–90.
  17. Malla, S., Dumre, S., Shakya, G., Kansakar, P., Rai, B., Hossain,. al, . e. (2014). The challenges and successes of implementing a sustainable antimicrobial resistance surveillance programme in Nepal. BMC Public Health., 14, 269.
  18. Morgan, D. J., Okeke, I. N., Laxminarayan, R., Perencevich, E. N., & Weisenberg, S. (2011). Non-prescription antimicrobial use worldwide: a systematic review. Lancet Infect. Dis., 11, 692-701.
  19. Nellums, L. B., Thompson, H., Holmes, A., Castro-Sanchez, E., Otter, J. A., & Norredam, M. (2018). Antimicrobial resistance among migrants in Europe''a systemic review and meta-analysis. THE LANCET: Infectious Diseases, 786-811.
  20. Okeke, I., Laxminarayan, R., Bhutta, Z., Duse, A., Jenkins, P., O’Brien, T.,. Klugman, K. (2005). Antimicrobial resistance in developing countries. Part I: recent trends and current status. Lancet Infect Dis, 5(8), 481-493.
  21. Parker, H., & Mattick, K. (2016). The determinants of antimicrobial prescribing among hospital doctors in England: a framework to inform tailored stewardship nterventions. Br J Clin Pharmacol, 82, 431.
  22. Pavydė, E., Veikutis, V., Mačiulienė, A., Mačiulis, V., Petrikonis, K., & Stankevičius, E. (2015). Public Knowledge, Beliefs and Behavior on Antibiotic Use and Self-Medication in Lithuania. International Journal of Environmental Research and Public Health, 7002-7016. doi:10.3390/ijerph120607002
  23. Pham-Duc, P., Cook, M. A., Cong-Hong, H., Nguyen-Thuy, H., Padungtod, P., Nguyen-Thi, H., & Dang-Xuan, S. (2019). Knowledge, attitudes and practices of livestock and aquaculture producers regarding antimicrobial use and resistance in Vietnam. PLOS ONE, 01-12. doi:10.1371/journal.pone.0223115
  24. Poku, A. K., Boamah, E. A., Abdula, M. A., Buabeng, K. O., Mahama, E., Dzabeng, F.,. Gyansa-Lutterodt, M. (2017). Knowledge of antibiotic resistance and antibiotic prescription practices among prescribers in the Brong Ahafo Region of Ghana; a cross-sectional study. BMC Health Services Research, 17, 422.
  25. Preethi, M., & Lakshmi, T. (2017). Survey on Knowledge, Attitude and Practice of Antimicrobial Resistance among Dental Students. Int. J. Pharm. Sci., 43(2), 5-7.
  26. Qavi, A., Segal-Maurer, S., Mariano, N., Urban, C., Rosenberg, C., Burns, J.,. Rahal, J. (2010). A survey of physicians’ knowledge and attitudes regarding antimicrobial resistance and antibiotic prescribing practices at the University Hospital of the West Indies. West Indian Med J., 59, 165–170.
  27. Ready, D., Lancaster, H., Qureshi, F., Bedi, R., Mullany, P., & Wilson, M. (2004). Effect of amoxicillin use on oral microbiota in young children. Antimicrob Agents Chemother., 48(8), 2883-7.
  28. Reardon, S. (2014). Antibiotic resistance sweeping developing world. Nature, 509, 141-142.
  29. San Francisco, C., Toro, M., Cobo, J., de Ge-Garcia, J., Vano-Galvan, S., Moreno-Ramos, F.,. Pano-parodo, J. (2013). Knowledge and perceptions of junior and senior Spanish resident doctors about antibiotic use and resistance: Results of a multicenter survey. Enferm infecc Microbiol Clin, 31, 199–204.
  30. Shehadeh, M., Suaifan, G., Darwish, R. M., Wazaify, M., Zaru, L., & Aliafari, S. (2011). Knowledge, attitude, and behavior regarding antibiotic use and misuse among adults in the community of Jordon: A Pilot Study. King Saud University Saudi Pharmaceutical Journal, 1319-0164.
  31. Tevatia, S., Chaudhry, S., Rath, R., & Dodwad, V. (2016). A QUESTIONNAIRE BASED SURVEY ON KNOWLEDGE, ATTITUDE AND PRACTICE OF ANTIBIOTICS AMONG DENTAL AND PARAMEDICAL STUDENTS- A CROSS SECTIONAL SURVEY. WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, 5(5), 1205-1216.
  32. Thriemer, K., Katuala, Y., Batoko, B., Alworonga, J., Devlier, H., VanGeet, C., .Jacobs, J. (2013). Antibiotic Prescribing in DR Congo: A Knowledge. Attitude and Practice Survey among Medical Doctors and Students. PLoS One, 8, 455-495. doi:0.1371/journal.pone.0055495
  33. Ying, H. J., Jiarui, G., Mingyu, Z., Zheng, R., Weldong, Y., Yang, C., & .. Fengmin, Z. (2013). Knowledge, attitude, and practice of antibiotics: a questionnaire study among 2500 Chinese students. Ying, H., Jiarui, G., Mingyu, Z., Zheng, R., Weldong, Y., Yang, C.,. Fengmin, Z. (2013). Knowledge, attitude, and practice of anti BMC Medical Education Journal, 01-09.

International Journal of Scientific Research in Chemistry

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Published

2022-08-05

Issue

Volume 7, Issue 4, July-August-2022

Section

Research Articles

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How to Cite

[1]
Plenseh Diana Paye, James McClain, " Knowledge, Attitude and Practice of antibiotics Resistance survey among healthcare professionals in selected health centers in Greater Monrovia, Liberia, International Journal of Scientific Research in Chemistry(IJSRCH), ISSN : 2456-8457, Volume 7, Issue 4, pp.01-13, July-August-2022.