Useful Medicinal Plants having Anti-Cancerous and Anti-Tumorous Medicinal Potential of Withania somnifera (L.) Dunai, Androgarphis paniculata(Burm.f.) Nees, and Glycyrrhiza globra (L.)

Authors

  • Pawan Kumar Sagar  Drug Standardization Research Institute, (CCRUM., Ministry of AYUSH.), PLIM., Campus, Kamlanehru nagar, Ghaziabad, Uttar Pradesh, India
  • Asma Sattar Khan  Drug Standardization Research Institute, (CCRUM., Ministry of AYUSH.), PLIM., Campus, Kamlanehru nagar, Ghaziabad, Uttar Pradesh, India
  • Ram Pertap Meena  Central Council for Research of Unani Medicine, Ministry of AYUSH., Janakpuri, D-Block, New Delhi, India
  • Suryansh Kashyap  Drug Standardization Research Institute, (CCRUM., Ministry of AYUSH.), PLIM., Campus, Kamlanehru nagar, Ghaziabad, Uttar Pradesh, India

Keywords:

Anti-cancerous, Anti-tumorous, ASU medicinal plants, bio-actives constituents, secondary metabolites, bioavailable, ethno-botany, effective biological activities

Abstract

Cancer is the one of the dangerous disease that causes death worldwide under the curent life style scenario. An study has been made to review important ASU medicinal plants which is traditionally used from last ancient time for the treatment and prevention of several harmful diseases from Sothern, North east and Himalayan region of India. Several synthetic agents are used to cure the disease but they have their adverse side effects, low healing potential and associated toxicity is challenging task hence the research is going on focus to investigate the bioavailable plant derived chemotherapeutic agents.This article considered of selective 3 medical plants Withania sominifera (L.) Dunai, Androgarphis paniculata(Burm.f.) Nees, and Glycyrrhiza globra (L.) from the India having effective anti-cancerous and anti-tumorous properties.These plants contain several anti-cancerous and anti-tumorous bio-actives constituents, secondary metabolites such as strong Withanolides and Withaferins-A, D along with a few other metabolites including Withanone and Withanosides, Steroidal lactones, Adriamycin and 5-fluorouracil in Withania sominifera (L.) Dunai and Andrographolide, ?-Sitosterol, Stigma Sterol, Chlorophylla, 5-2-dihydroxy-7,8-dimethoxy-flavone,?-Sitosteryl fatty acid ester, lupeol, Triacylglycerols in Androgarphis paniculata(Burm.f.) Nees and Glycyrrhezic acid, 18?-Glycyrrhetic acid, Glycyrrhizin, Anethole (3% to total volatile), Iso- flavone Glabreneonl, Iso-flavone glaberidin, Licochalcone-A, licoagrochalcone in Glycyrrhiza globra (L.), these selective medicinal plants screening have been shown to prevent and inhibit grouth of cancers and tumors growth which has confirmed in several in-vitro and in-vivo Cancer cell line studies.This study also reveales and incorporates the ethno-botany pharmacological and biological activities,Current research provide referencial support of novel drug discovery, pharmacopial standared development and future perspectives of these selective important medicinal plants.

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International Journal of Scientific Research in Chemistry

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2023-01-01

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Pawan Kumar Sagar, Asma Sattar Khan, Ram Pertap Meena, Suryansh Kashyap, " Useful Medicinal Plants having Anti-Cancerous and Anti-Tumorous Medicinal Potential of Withania somnifera (L.) Dunai, Androgarphis paniculata(Burm.f.) Nees, and Glycyrrhiza globra (L.), International Journal of Scientific Research in Chemistry(IJSRCH), ISSN : 2456-8457, Volume 8, Issue 1, pp.11-26, January-February-2023.