Synthesis, Characterization and Antimicrobial Activity of Metal Complexes prepared from Schiff Base Ligand
Keywords:
Metal Complexes, Antifungal Activity, Schiff BaseAbstract
Coordination compounds of some transition metal ions Co(II) of synthesized ligand 4-chloro-2-(((4-chlorophenyl) imino)methyl) phenol. These Schiff base ligand were characterized by elemental analysis, FTIR, UV-Vis, 1H-NMR, 13CNMR, Mass spectral analysis ,magnetic susceptibility and molar conductance, whereas, Metal complexes is analyzed by IR, UV-Vis, Magnetic susceptibility, Molar Conductance, elemental analysis.Schiff base ligand and its metal (II) complexes were tested in vitro to evaluate their bactericidal activity against bacteria S. aureus and B.subtilis and antifungal activity against A. Niger and F. Oxysporum using the Kirby-Bauer disc diffusion method. antibacterial evaluation results revealed that the metal (II) complexes exhibited higher antibacterial activity than the free Schiff base ligand.
References
Elango, G., Arumugam, A., & Guhanathan, S. (2017). Co (II), Ni (II) and Cu (II) Complexes with Schiff Base Ligand: Syntheses, Characterization, Antimicrobial Studies and Molecular Docking Studies. SOJ Mater. Sci. Eng, 5, 1-12.
Dalia, S. A., Afsan, F., Hossain, M. S., Khan, M. N., Zakaria, C., Zahan, M. E., & Ali, M. (2018). A short review on chemistry of schiff base metal complexes and their catalytic application. Int. J. Chem. Stud, 6(3), 2859-2867.
Joseyphus, R. S., & Nair, M. S. (2008). Antibacterial and antifungal studies on some schiff base complexes of zinc (II). Mycobiology, 36(2), 93-98.
Akitsu, T. (Ed.). (2023). Schiff Base in Organic, Inorganic and Physical Chemistry. BoD–Books on Demand.
Juyal, V. K., Pathak, A., Panwar, M., Thakuri, S. C., Prakash, O., Agrwal, A., & Nand, V. (2023). Schiff base metal complexes as a versatile catalyst: A review. Journal of Organometallic Chemistry, 122825.
Gupta, K. C., & Sutar, A. K. (2008). Catalytic activities of Schiff base transition metal complexes. Coordination Chemistry Reviews, 252(12-14), 1420-1450.
Ispir, E. (2009). The synthesis, characterization, electrochemical character, catalytic and antimicrobial activity of novel, azo-containing Schiff bases and their metal complexes. Dyes and Pigments, 82(1), 13-19.
Boulechfar, C., Ferkous, H., Delimi, A., Djedouani, A., Kahlouche, A., Boublia, A., ... & Benguerba, Y. (2023). Schiff bases and their metal Complexes: A review on the history, synthesis, and applications. Inorganic Chemistry Communications, 150, 110451.
Maher, K. A., & Mohammed, S. R. (2015). Metal complexes of Schiff base derived from salicylaldehyde-A review. International Journal of Current Research and Review, 7(2), 6.
Abu-Dief, A. M., & Mohamed, I. M. (2015). A review on versatile applications of transition metal complexes incorporating Schiff bases. Beni-suef university journal of basic and applied sciences, 4(2), 119-133.
Kumar, R., Singh, A. A., Kumar, U., Jain, P., Sharma, A. K., Kant, C., & Faizi, M. S. H. (2023). Recent advances in synthesis of heterocyclic Schiff base transition metal complexes and their antimicrobial activities especially antibacterial and antifungal. Journal of Molecular Structure, 1294, 136346.
Rani, M., Devi, J., Kumar, B., & Rathi, M. (2024). Unveiling Anti‐malarial, Antimicrobial, Antioxidant Efficiency and Molecular Docking Study of Synthesized Transition Metal Complexes Derived From Heterocyclic Schiff Base Ligands. Chemistry–An Asian Journal, 19(19), e202400676.
Sandhu, Q. U. A., Pervaiz, M., Majid, A., Younas, U., Saeed, Z., Ashraf, A., ... & Jelani, S. (2023). Schiff base metal complexes as anti-inflammatory agents. Journal of Coordination Chemistry, 76(9-10), 1094-1118.
Uddin, M. N., Ahmed, S. S., & Alam, S. R. (2020). Biomedical applications of Schiff base metal complexes. Journal of Coordination Chemistry, 73(23), 3109-3149.
Parashar, R. K., Sharma, R. C., Kumar, A., & Mohan, G. (1988). Stability studies in relation to IR data of some schiff base complexes of transition metals and their biological and pharmacological studies. Inorganica chimica acta, 151(3), 201-208.
Liu, X., Manzur, C., Novoa, N., Celedón, S., Carrillo, D., & Hamon, J. R. (2018). Multidentate unsymmetrically-substituted Schiff bases and their metal complexes: Synthesis, functional materials properties, and applications to catalysis. Coordination Chemistry Reviews, 357, 144-172.
Lumb, I., Sran, B. S., Sood, H., Arora, D. S., & Hundal, G. (2017). Coordination chemistry of Cu (II), Co (II), Zn (II) and Ag (I) complexes of isomeric pyridine 2-and 4-carboxamides and their biological activity evaluation. Polyhedron, 127, 153-166.
Hashem, H. E., Nath, A., & Kumer, A. (2022). Synthesis, molecular docking, molecular dynamic, quantum calculation, and antibacterial activity of new Schiff base-metal complexes. Journal of Molecular Structure, 1250, 131915.
El-Gammal, O. A., Mohamed, F. S., Rezk, G. N., & El-Bindary, A. A. (2021). Synthesis, characterization, catalytic, DNA binding and antibacterial activities of Co (II), Ni (II) and Cu (II) complexes with new Schiff base ligand. Journal of Molecular Liquids, 326, 115223.
Zaidan, M. R., Noor Rain, A., Badrul, A. R., Adlin, A., Norazah, A., & Zakiah, I. (2005). In vitro screening of five local medicinal plants for antibacterial activity using disc diffusion method. Trop biomed, 22(2), 165-170.
Ommenya, F. K., Nyawade, E. A., Andala, D. M., & Kinyua, J. (2020). Synthesis, Characterization and Antibacterial Activity of Schiff Base, 4‐Chloro‐2‐{(E)‐[(4‐Fluorophenyl) imino] methyl} phenol Metal (II) Complexes. Journal of Chemistry, 2020(1), 1745236.
Orlova, N., Nikolajeva, I., Pučkins, A., Belyakov, S., & Kirilova, E. (2021). Heterocyclic schiff bases of 3-Aminobenzanthrone and their reduced analogues: Synthesis, properties and spectroscopy. Molecules, 26(9), 2570.
Kareem, M. J., Al‐Hamdani, A. A. S., Jirjees, V. Y., Khan, M. E., Allaf, A. W., & Al Zoubi, W. (2021). Preparation, spectroscopic study of Schiff base derived from dopamine and metal Ni (II), Pd (II), and Pt (IV) complexes, and activity determination as antioxidants. Journal of physical organic chemistry, 34(3), e4156.
Tolan, D. A., Kashar, T. I., Yoshizawa, K., & El‐Nahas, A. M. (2021). Synthesis, spectral characterization, density functional theory studies, and biological screening of some transition metal complexes of a novel hydrazide–hydrazone ligand of isonicotinic acid. Applied Organometallic Chemistry, 35(6), e6205.
El Saied, F. A., Shakdofa, M. M., El Tabl, A. S., & Abd Elzaher, M. M. (2014). Coordination behaviour of N′ 1, N′ 4-bis ((1, 5-dimethyl-3-oxo-2-phenyl-2, 3-dihydro-1H-pyrazol-4-yl) methylene) succinohydrazide toward transition metal ions and their antimicrobial activities. Main Group Chemistry, 13(2), 87-103.
Boghaei, D. M., Askarizadeh, E., & Bezaatpour, A. (2008). Synthesis, characterization, spectroscopic and thermodynamic studies of charge transfer interaction of a new water-soluble cobalt (II) Schiff base complex with imidazole derivatives. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 69(2), 624-628.
Shakir, M., Azim, Y., & Parveen, S. (2006). Synthesis, characterization of complexes of Co (II), Ni (II), Cu (II) and Zn (II) with 12-membered Schiff base tetraazamacrocyclic ligand and the study of their antimicrobial and reducing power. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 65(2), 490-496.
Mohamed, G. G., Zayed, M. A., & Abdallah, S. M. (2010). Metal complexes of a novel Schiff base derived from sulphametrole and varelaldehyde. Synthesis, spectral, thermal characterization and biological activity. Journal of Molecular Structure, 979(1-3), 62-71.
Devi, J., Sharma, S., Kumar, S., Kumar, B., Kumar, D., Jindal, D. K., & Das, S. (2022). Synthesis, characterization, in vitro antimicrobial and cytotoxic studies of Co (II), Ni (II), Cu (II), and Zn (II) complexes obtained from Schiff base ligands of 1, 2, 3, 4‐tetrahydro‐naphthalen‐1‐ylamine. Applied Organometallic Chemistry, 36(8), e6760.
Ferraro, J. R. (2012). Low-frequency vibrations of inorganic and coordination compounds. Springer Science & Business Media.
Nakamoto, K. (2009). Infrared and Raman spectra of inorganic and coordination compounds, part B: applications in coordination, organometallic, and bioinorganic chemistry. John Wiley & Sons.
Kavitha, N., & Lakshmi, P. A. (2017). Synthesis, characterization and thermogravimetric analysis of Co (II), Ni (II), Cu (II) and Zn (II) complexes supported by ONNO tetradentate Schiff base ligand derived from hydrazino benzoxazine. Journal of Saudi Chemical Society, 21, S457-S466.
Hammam, A. M., El-Gahami, M. A., Khafagi, Z. A., Al-Salimi, M. S., & Ibrahim, S. A. (2015). Synthesis and characterization of some new antimicrobial transition metal complexes with 1, 2, 4-Traizole-3-thione schiff bases. J. Mater. Environ. Sci, 6(6), 1596-1605.
Yousif, E., Majeed, A., Al-Sammarrae, K., Salih, N., Salimon, J., & Abdullah, B. (2017). Metal complexes of Schiff base: preparation, characterization and antibacterial activity. Arabian Journal of Chemistry, 10, S1639-S1644.
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